In a case study of over 4,600 incidents of upper respiratory tract infections, only 5% of cases treated with spinal manipulative therapy developed secondary complications. As shown in this study, the results are superior to those obtained by antimicrobial therapy or symptomatic therapy alone. It would seem unnecessary to use any therapy other than manipulative therapy. Prescribing anti microbial agents because of uncertainty of diagnosis or because of pressure from the family is no substitute for application of good principles of medicine.
Purse FM. J Am Osteopath Assoc 1966 (May);65 (9): 964-972