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Aspartame, a widely used artificial sweetener, was administered with feed to male and female Sprague-Dawley rats (100–150/sex/group), 8 weeks-old at the start of the experiment, at concentrations of 100,000; 50,000; 10,000; 2,000; 400; 80 and 0 ppm. Treatment lasted until spontaneous death of the animals.
In this report we present the first results showing that aspartame, in our experimental conditions, causes a statistically significant, dose-related increase in lymphomas and leukaemias in females.
No statistically significant increase in malignant brain tumors was observed among animals from the treated groups as compared to controls.
Eur. J. Oncol., 10 (2), 00-00, 2005
This article appeared in Pathways to Family Wellness magazine, Issue #07.
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