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Home Wellness Research General Health and Life Styles Protection at Birth: Rub in the Vernix

Protection at Birth: Rub in the Vernix

Monday, 03 November 2008 15:07
The newborn infant is protected by an innate antimicrobial barrier: peptide antibiotics are present in the skin and vernix caseosa

Peptide antibiotics are part of the surface defenses against microbial intruders. However, the presence and significance of these innate immune effectors in the skin barrier of the newborn infant have not yet been appreciated.

Peptide antibiotics are present in the vernix caseosa and in the skin of the healthy newborn infant, indicating effective innate immune protection already during fetal and neonatal life.

G. Marchini, S. Lindow, H. Brismar, B. Ståbi, V. Berggren, A-K. Ulfgren,* S. Lonne-Rahm, B. Agerberth and G.H. Gudmundsson