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Home Wellness Research Ritalin Ritalin Treatment During Pre- and Periadolescence Affects Responses to Emotional Stimuli at Adulthood

Ritalin Treatment During Pre- and Periadolescence Affects Responses to Emotional Stimuli at Adulthood

Monday, 03 November 2008 16:48

Methylphenidate (MPH) is a psychomotor stimulant medication widely used for the treatment of attention -deficit/hyperactivity disorder (ADHD). Given the extent of prescribed use of MPH, and because MPH interacts with the same brain pathways activated by drugs of abuse, most research has focused on assessing MPH's potential to alter an individual's risk for adult drug addiction.

Chronic exposure to MPH during development leads to decreased sensitivity to rewarding stimuli while resulting in enhanced responsivity to aversive situations. These results highlight the need for further research to better understand the effects of stimulants on the developing nervous system, and the potential enduring effects resulting from early-life drug exposure.

Biological Psychiatry