Clinical Evidence Shows Limited Effect of Antibiotic Treatment on Children With Acute Otitis Media

A study conducted by the Southern California/RAND Evidence-based Practice Center (EPC) and sponsored by the Agency for Healthcare Research and Quality reveals that nearly two-thirds of children with uncomplicated acute otitis media recover from pain and fever within 24 hours of diagnosis without treatment with antibiotics. And, over 80% recover within 1-7 days. When treated with antibiotics, up to 93% of children recover during the first week.
Investigators found no evidence that children with acute otitis media treated with amoxicillin fared any differently from those treated with newer, more aggressive antibiotics - which are more expensive and more likely to provoke side effects.

Press Release, August 9, 2000   Clinical Evidence Shows Limited Effect of Antibiotic Treatment on Children With Acute Otitis Media   Agency for Healthcare Research and Quality, Rockville, MD.

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